姓    名

程一民

性    别

男

出生年月

1992.11

学科专业

生物学

毕业院校

南昌大学

学    位

博士

职    称

助理研究员

现任职务

无

联系电话

13767576013

电子邮件

1169331029@qq.com

研究领域与方向

生殖医学（男性不育症的发病机制）

科研课题（主要承担和参与的科研项目）

1. 赖氨酸戊二酰化修饰调控人精子运动的分子机制及其在弱精症中的作用（国家自然科学基金青年项目，负责人，基金号:82101690）；

2. 新型蛋白修饰Khib与弱精症相关性的临床研究（江西省卫生健康委员会科技项目，负责人）；

3. 弱精症相关hPAQR7受体在人精子孕酮信号转导中的作用机制（国家自然科学基金面上项目，参与）；

4. PAQR7在精子响应孕酮能力下降的男性不育症中的作用机制（国家自然科学基金面上项目，参与）；

5. 基于精子特异性嗅觉受体OR1D2研究人精子趋化机制（国家自然科学基金面上项目，参与）。

代表性学术论著 (译著、教材)、论文

1.   Yi-min Cheng,   Peng Z, et al. Lysine 2-hydroxyisobutyrylation   of tail proteins affects human sperm motility. Human Reproduction (SCI一区). 2020 March; 3:3. IF=7.

2.   Yi-min Cheng,   Hu X-N, et al. Lysine glutarylation in human sperm is associated with   progressive motility. Human Reproduction   (SCI一区). 2019 April; 34:1186-1194.   IF=7.

3.   Yangyang   Yuan, Xinbao Ding, Yimin Cheng, Hang Kang, Tao Luo, Xiaoning Zhang, Hai   bin Kuang. PFOA   evokes extracellular Ca²⁺influx and compromises   progesterone-induced response in human sperm.Chemosphere, SCI二区,   2020;   241: 125074. IF=7.1.

4.   Rennhack,   Schiffer, Benker, Fridman, Nitao, Yi-min Cheng, Berger, Zeng XH, Publicover,   Kaupp, Timo.A novel cross-species inhibitor to study the function of CatSper Ca2+   channels in sperm.British Journal of Pharmacology (SCI一区). 2018 April; 175(15).   (同德国实验室合作完成), IF=7.73.

5. Luo T,   Hou-yang Chen, Qian-xing Zou, Tao Wang, Yi-min   Cheng. A novel copy number variation in CATSPER2 causes   idiopathic male infertility with normal semen parameters. Human   Reproduction (SCI一区). 2018 Nov;34 (3):   414-423. IF=7.

6. Zou   QX, Peng Z, Zhao Q, Chen HY, Yi-min Cheng, Liu Q, He YQ, Weng SQ, Wang HF, Wang T, Luo T. Diethylstilbestrol activates   CatSper and disturbs progesterone actions in human spermatozoa.Human Reproduction (SCI一区). 2017 Feb; 32(2):290-298.IF=7.

7. Meng-ge Lv, Wen-qiong   Chen, Shi-qi Weng, Hou-yang Chen, Yi-min Cheng, Tao Luo. Rosmarinic   acid compromises human sperm functions by an intracellular Ca²⁺   concentration-related mechanism., Reproductive   Toxicology (SCI三区). 2018 July; 81:58-63.   IF=3.2. 

8.   Wang HF,   Chang M, Peng TT, Yang Y, Li N, Luo T, Yi-min Cheng, Zhou MZ, Zeng XH,   Zheng LP. Exposure to Cadmium impairs sperm functions by reducing CatSper in mice.,   Cell Physi Biochem (SCI二区).   2017   March; 42: 44-54. IF=5.5

9.   Kang H,   Zhao N, Yi-min Cheng, Zeng XH. Sperm chemotaxis in marine invertebrates   and mammals. Reproductive and   developmental Medicine. 2017 June; 1:115-9.

10.   Diao RY,   Wang T, Kin Lam Fok, Li XF, Ruan YC, Yu MK, Yi-min Cheng, Chen Y, Chen   H, Mou LS, Cai XY, Wang Y. CCR6 is required for ligand-induced CatSper activation   in human sperm. Oncotarget. 2017   Oct; 8(53):91445-91458.

学术兼职及荣誉称号

无

发明专利及获奖情况

国家发明专利：用于制备mPRα单克隆抗体的免疫原；专利号：ZL 2019 1 0552308. X