药学硕导

方文捷(临床药学)

发布时间:2026-05-09浏览次数: 10

方文捷副主任医师,副教授,副研究员医学博士,荷兰皇家科学院国家公派联合培养博士。现任上海市医师协会皮肤病分会委员、中国人口文化促进会皮肤病分会秘书长、人卫健康知识库专家委员会特约委员。入选军队高层次青年科技英才、海军优秀文职科技人才,上海市东方英才、上海市医苑新星、上海市扬帆计划等8项人才计划。担任iFungi(eISSN 3079-7284)创刊执行主编、Mycology(IF=4.9)编委、《中华诊断学电子杂志》编委、中国真菌学杂志》编委、iMeta(IF=33)JTIM(IF7.4)青年编委。

近年来主持国自然、国家重点研发计划课题、国家传染病重大专项子课题等16项课题,第一/通讯作者(含并列)发表SCI论文25篇,包括STTT, Redox Biol, JAAD等期刊,其中中科院一区TOP期刊3篇,他引2200+次,ESI高引2篇,封面论文1篇,H指数24。第一发明人专利成果转化3项,获批医疗器械证2项,主编中英文论著5部,副主编2部,《军事皮肤病学》副主编,参编国家规划教材2部。主笔专家共识1项,参与国家级标准1项。以主要完成人获教育部科技进步一等奖(排名4)、河北省科技进步三等奖(排名4)和华夏医学科技一等奖(排名5)Weliy高贡献作者奖。邮箱:fangwenjie1990@126.com

主持项目

1.国家自然科学基金青年项目(82202543):"肺肠轴"微生物结构特征与肺移植术后侵袭性肺曲霉病的关联研究

2.国家重点研发计划课题(2022YFC2504800):我国皮肤真菌病综合防治体系及关键技术研究

3.国家科技重大专项后补助项目子课题(2020ZX10001015-06):侵袭性真菌病生物样本库和专病登记平台的建立和应用

主持主要代表性成果

1.Wu J, Li C, Gao P, Zhang C, Zhang P, Zhang L, Dai C, Zhang K, Shi B, Liu M, Zheng J, Pan B, Chen Z, Zhang C, Liao W, Pan W, Fang W, Chen C. Intestinal microbiota links to allograft stability after lung transplantation: a prospective cohort study. Signal Transduct Target Ther. 2023 Sep 1;8(1):326. doi: 10.1038/s41392-023-01515-3. PMID: 37652953; PMCID: PMC10471611. (共同通讯作者,SCI,中科院1TopIF 40.2

2.Liu X, Guo S, Wang J, Zhang L, Lin Y, Liu Y, Ouyang J, Shi D, Xu B, Fang W, Ran Y. Caged-hypocrellin-mediated antimicrobial photodynamic therapy as a dual-action strategy for fungal clearance and immune response regulation in drug-resistant Candida auris wound infections. J Am Acad Dermatol. 2026 Jan;94(1):73-80. doi: 10.1016/j.jaad.2025.08.040. Epub 2025 Aug 22. PMID: 40850383. (共同通讯作者,SCI,中科院1TopIF 10.8

3.Liu X, Tao Y, Zhang L, Liu Y, Shi D, Wang J, Xue P, Xu B, Fang W, Ran Y. Caged-hypocrellin mediated photodynamic therapy induces chromatin remodeling and disrupts mitochondrial energy metabolism in multidrug-resistant Candida auris. Redox Biol. 2025 Sep;85:103708. doi: 10.1016/j.redox.2025.103708. Epub 2025 Jun 14. PMID: 40544603; PMCID: PMC12221887. (共同通讯作者,SCI,中科院1TopIF 10.9

4.Fang W, Wu J, Cheng M, Zhu X, Du M, Chen C, Liao W, Zhi K, Pan W. Diagnosis of invasive fungal infections: challenges and recent developments. J Biomed Sci. 2023 Jun 19;30(1):42. doi: 10.1186/s12929-023-00926-2. PMID: 37337179; PMCID: PMC10278348. (第一作者,SCI,中科院1TopIF 12

5.Zhu X, Zhang C, Jiang W, Zeng Z, Zhang K, Du M, Chen J, Wu Q, Liao W, Chen Y, Fang W, Pan W. Trem2 acts as a non-classical receptor of interleukin-4 to promote diabetic wound healing. Clin Transl Med. 2024 Oct;14(10):e70026. doi: 10.1002/ctm2.70026. PMID: 39350473; PMCID: PMC11442487. (共同通讯作者,SCI,中科院2区,IF 6.8

6.Zhang TY, Lu EP, Lin Y, Zhou JA, Chen Y, Qi WJ, Guo J, Cheong IH, Wong KH, Kozlakidis Z, Moore GG, Pan W, Liao W, Fang W, Chen CB, Lu L, Wu W, Liu NN. Factoring fungi into the One Health conversation. Fundam Res. 2026 Jan 24. Epub ahead of print. https://doi.org/10.1016/j.fmre.2026.01.006(共同通讯作者,SCI,中科院2区,IF 6.3

7.Daneshnia F, Cai L, Gunasekaran D, Gautam I, Perry AM, Mosharaf Ghahfarokhy P, Ebadati A, Munoz J, Padilla D, Hilmioglu-Polat S, Mei S, Floyd DJ, Schikora-Tamarit MÀ, Funtes D, Artigues-Lleixà M, Walker LA, Gonçalves SM, Salehi M, Carvalho A, Desai JV, Perlin DS, Munro CA, Hopke A, Wang T, Gabaldón T, Fang W, Nobile CJ, Mansour MK, Arastehfar A. Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity. Microbiol Spectr. 2026 Feb 13:e0304325. doi: 10.1128/spectrum.03043-25. Epub ahead of print. PMID: 41685898. (共同通讯作者,SCI,中科院2区,IF 3.8

8The New Era of Fungal Infection Diagnosis,主编,MedCore Press出版社

9Constructivist Approaches in Dermatovenereology Education: Bridging Theory and Practice,主编,AccScience Press出版社

10.病毒性肺炎继发真菌感染的防控,主编,科学出版社

11.高危真菌生物安全威胁及应对,副主编,科学出版社

获奖情况

12021年,我国与“一带一路”沿线国家重要真菌病防控关键技术和应用,教育部科技进步奖,一等奖(第四完成人)

22021年,状态人群隐球菌感染临床调查及真菌病诊断关键技术应用,河北省科技进步奖,三等奖(第四完成人)

32017年,发真菌病的传播机制及临床诊治,华夏医学科技奖,一等奖(第五完成人)