乐敏，教授博士／博导，国家级人才计划（第十三批/2017），联合国FAO/WHO Roster expert（2023-2027），PPLI fellow，省海外高层次人才引进计划特聘专家（2018），省杰出青年基金获得者（2019）；2010.7-2017.2美国宾夕法尼亚大学工作（博士后和副研究员）；中国微生物学会兽医微生物学专业委员会委员，中国畜牧兽医学会兽医食品卫生学分会常务理事，中国畜牧兽医学会动物微生态分会常务理事；担任PLoS Pathogens，mSystems，Foodborne Pathog Dis， Front Microbiol， Front Vet Sci，Microorganisms，Research，iMeta，mLife，hLife，Animal Dis，Animals&Zoonosis, Animal Research&One Health等杂志学术编委或副主编。
一直致力于病原基因组与生物安全研究。聚焦人兽共患病菌——沙门菌，利用微生物组等大数据分析并结合系统生物学手段，解析了病菌流行传播规律，揭示了病菌跨种感染与持续感染机制，构建了病原大数据预警与风险评估平台。承担国家重点研发计划课题和国家基金等十余项，以通讯作者在Nature Med，Lancet PlanetHealth，Natl Sci Rev，Nat Commun（3 篇），EMBO Mol Med，Clinical Infect Dis（2 篇），mBio 等发表论文100 余篇（其中IF5>10 论文20 余篇），累计引用6000 余次，ESI 高被引论文七篇；申报/授权国家发明专利10 余件，制定团体标准2 套。邮箱：myue@ucas.ac.cn
主持项目
国家自然科学基金- 31972166
省自然科学基金重点项目，省科技厅LZ24C180002
国家重点研发计划子课题，科技部-2022YFC2604201
省自然科学基金（联合项目）2021JJLH0083
省重点研发计划课题-2022C02024
省重大项目课题-2021C02008
省重点研发计划课题-2020C02032
国家重点研发计划子课题，科技部-2018YFD0500501
国家重点研发计划课题，科技部- 2017YFC1600103
主要代表性成果
1. Zhou H, Jia C, Shen P, Huang C, Teng L, Wu B, Wang Z, Wang H, Xiao Y, Baker S, Weill FX, Li Y, Yue M* (2025) Genomic Census of Invasive Non-typhoidal Salmonella Infections Reveals Global and Local Human-to-Human Transmission. Nature Medicine 31(7):2325-2334. doi:10.1038/s41591-025-03644-4. (IF5: 52.4) 医学1区Top
BioArt Highlight [Nat Med | 乐敏课题组揭示侵袭性非伤寒沙门菌“人传人”新模式]
2. Zhou X, Kang X, Chen J, Song Y, Jia C, Teng L, Tang Y, Jiang Z, Peng X, Tao X, Xu Y, Huang L, Xu X, Xu Y, Zhang T, Yu S, Gong J, Wang S, Liu Y, Zhu G, Kehrenberg C, Weill FX, Barrow P, Li Y, Zhao G, Yue M* (2023) Genome degradation promotes Salmonella pathoadaptation by remodeling fimbriae-mediated proinflammatory response. National Science Review 10(10): nwad228. doi: 10.1093/nsr/nwad228. (IF5: 17.7) 综合性1区Top
BioArt Highlight [NSR | “以退为进”实现“双赢”，乐敏课题组揭示病原菌宿主适应新机制]
腾讯科研进展[浙大乐敏课题组以鸡白痢沙门菌为模型提出病原菌宿主适应“以退为进”新机制]
ZJU Highlight [动科学院乐敏课题组揭示病原菌宿主适应“以退为进”新机制]
3. Jia C, Zhou H, Chao Q, Huang C, An H, Li Y, Lan L, Yue M* (2026) Distinct Genomic Trajectory among Invasive Salmonella Typhimurium ST313 Infections. Nature Communications Mar 9; doi: 10.1038/s41467-026-70196-7. (IF5: 17.2) 综合性1区Top BioArt Highlight [Nat Commun丨乐敏组揭示侵袭性沙门菌的全球演化与“侵袭性”致病机制]
https://www.163.com/dy/article/KOAO9L8D0532BT7X.html
4. Li Y, Teng L, Xu X, Li X, Peng X, Zhou X, Du J, Tang Y, Jiang Z, Wang Z, Jia C, Müller A, Kehrenberg C, Wang H, Wu B, Weill FX, Yue M* (2022) A non-typhoidal Salmonella serovar domestication accompanying enhanced niche adaptation.EMBO Molecular Medicine 14(11):e16366. doi: 10.15252/emmm.202216366. (IF5: 10) 医学1区Top
5. Zhou Z, Teng L, Geng X, Qiao M, Xiao K, Zhao Z, Ba X, Achi C, Chen H, Li J, Gillings M, Topp E, Boeckel T, Gaze W, Qin Y, Holmes M, Walsh T, Yue M*, Zhu Y* (2026) Climate change accelerates the spread of antibiotic resistance genes in Salmonella: a global analysis derived from temperature, precipitation and socioeconomic factors. Lancet Planetary Health in press (IF5: 27.1) 医学1区Top
6. Li Y, Ed-Dra A, Tang B, Kang X, Müller A, Kehrenberg C, Jia C, Pan H, Yang H, Yue M* (2022) Higher tolerance of predominant Salmonella serovars circulating in the antibiotic-free feed farms to environmental stresses. Journal of Hazardous Materials 438:129476. doi: 10.1016/j.jhazmat.2022.129476. (IF5: 12.4) 环境生态1区TopESI highly cited paper
7. Tang L, Xie P, Wang H, Hong X, Gong Z, Zhao G, Yue M* (2025) The Sex Hormones-Gut Microbiome Axis: Mechanistic Drivers of Sex-Disparate Bacterial Infection Outcomes and Precision Clinical Interventions. Clinical Microbiology Review 38(4):e0023625. doi: 10.1128/cmr.00236-25. (IF5: 33.3) 医学1区Top
8. Lu Q, Feng Y, Wang H, Zhu K, Teng L, Yue M*, Li Y*. (2025) Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination. Gut Microbes 17(1):2563709. doi: 10.1080/19490976.2025.2563709. (IF5: 13.4) 医学1区
9. Liu Y, Peng Na, Yao Y, Zhang X, Peng X, Zhao L, Wang J, Peng L, Wang Z, Mochizuki K*, Yue M*, Yang S* (2022) Breaking the Nanoparticle’s Dispersible Limit via Rotatable Surface Ligands. Nature Communications 13(1):3581. DOI: 10.1038/s41467-022-31275-7. (IF5: 17.2) 综合性1区
10. Yue M, Han X, Masi LD, Zhu C, Ma X, Zhang J, Wu R, Schmieder R, Kaushik RS, Fraser GP, Zhao S, McDermott PF, Weill FX, Mainil JG, Arze C, Fricke WF, Edwards RA, Brisson D, Zhang NR, Rankin SC, Schifferli DM* (20151030) Allelic variation contributes to bacterial host specificity. Nature Communications 6:8754. DOI: 10.1038/ncomms9754. (IF5: 17.2) 综合性1区
